ABD’li biyoteknoloji \u015firketi Vaxart taraf\u0131ndan geli\u015ftirilen, tablet formunda a\u011f\u0131z yoluyla al\u0131nabilen potansiyel yeni tip koronavir\u00fcs (Kovid-19) a\u015f\u0131s\u0131n\u0131n klinik denemelerine ba\u015fland\u0131\u011f\u0131 bildirildi.<\/p>\n

“Clinical Trials Arena” internet sitesinde yer alan habere g\u00f6re, “VXA-CoV2-1” adl\u0131 Kovid-19 a\u015f\u0131 aday\u0131 insanlar \u00fczerinde test edilmeye ba\u015fland\u0131.<\/p>\n

Birinci a\u015fama klinik deneme kapsam\u0131nda a\u015f\u0131 aday\u0131 18 ila 54 ya\u015flar\u0131ndaki 48 sa\u011fl\u0131kl\u0131 g\u00f6n\u00fcll\u00fc \u00fczerinde iki doz olarak denenecek.<\/p>\n

A\u015f\u0131n\u0131n g\u00fcvenli olup olmad\u0131\u011f\u0131n\u0131n ve ba\u011f\u0131\u015f\u0131kl\u0131k etkisinin s\u0131nanaca\u011f\u0131 deneme s\u00fcresinde deneklere d\u00fc\u015f\u00fck ve y\u00fcksek dozlar i\u00e7eren a\u015f\u0131 \u00f6zellikli tabletler 28 g\u00fcn arayla verilecek.<\/p>\n

“VXA-CoV2-1”, Kovid-19’a kar\u015f\u0131 geli\u015ftirilen a\u015f\u0131 adaylar\u0131 aras\u0131nda tablet formundaki ilk \u00f6rnek oldu.<\/p>\n

A\u015f\u0131 aday\u0131n\u0131n, enjeksiyon yoluyla uygulanan muadillerine g\u00f6re, da\u011f\u0131t\u0131m ve geni\u015f kitlelere tatbik edilme bak\u0131m\u0131ndan kolayl\u0131klar sa\u011flayaca\u011f\u0131 \u00f6ng\u00f6r\u00fcl\u00fcyor.<\/p>\n

Enjeksiyon formunda uygulanan a\u015f\u0131lar\u0131n so\u011futucularda muhafaza edilmesi gerekirken tablet formundaki a\u015f\u0131 aday\u0131 oda s\u0131cakl\u0131\u011f\u0131nda saklanabiliyor.<\/p>\n

Daha \u00f6nce \u00c7in, 11 Eyl\u00fcl’de Hong Kong \u00dcniversitesi ara\u015ft\u0131rmac\u0131lar\u0131 taraf\u0131ndan geli\u015ftirilen burun spreyi formundaki Kovid-19 a\u015f\u0131 aday\u0131n\u0131n klinik denemelerine onay vermi\u015fti.<\/p>\n

Bir a\u015f\u0131n\u0131n yayg\u0131n olarak kullan\u0131labilmesi i\u00e7in 3 a\u015famada insanlar \u00fczerinde test edilmesi gerekiyor.<\/p>\n

Klinik denemelerin ilk a\u015famas\u0131nda, az say\u0131daki g\u00f6n\u00fcll\u00fc sa\u011fl\u0131kl\u0131 denek \u00fczerinde a\u015f\u0131n\u0131n g\u00fcvenli olup olmad\u0131\u011f\u0131 ve insanlar \u00fczerindeki muhtemel yan etkileri ara\u015ft\u0131r\u0131l\u0131yor. \u0130kinci a\u015famada, a\u015f\u0131n\u0131n ba\u011f\u0131\u015f\u0131k tepkilerini uyand\u0131rmadaki etkinli\u011fi 100\u2019den fazla denek \u00fczerinde test ediliyor. \u00dc\u00e7\u00fcnc\u00fc ve son a\u015famada ise ayn\u0131 i\u015flem binlerce denekle tekrarlan\u0131yor. T\u00fcm bu s\u00fcre\u00e7 aylar ve hatta y\u0131llar alabiliyor.<\/p>\n

D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc (DS\u00d6) verilerine g\u00f6re, 2 Ekim itibar\u0131yla d\u00fcnya genelinde Kovid-19’a kar\u015f\u0131 42 a\u015f\u0131 aday\u0131 klinik deneme, 151 a\u015f\u0131 aday\u0131 ise klinik \u00f6ncesi de\u011ferlendirme a\u015famas\u0131nda bulunuyor.<\/p>\n

Klinik denemeleri y\u00fcr\u00fct\u00fclen a\u015f\u0131lar\u0131n 10’u \u00fc\u00e7\u00fcnc\u00fc, 14’\u00fc ikinci, 18’si ise birinci a\u015famada insanlar \u00fczerinde test ediliyor.<\/p>\n

\u00c7in’de ortaya \u00e7\u0131kan Kovid-19, 200’den fazla \u00fclke ve b\u00f6lgeye yay\u0131larak k\u00fcresel salg\u0131na d\u00f6n\u00fc\u015ft\u00fc. D\u00fcnya genelinde vaka say\u0131s\u0131 38,4 milyonu a\u015farken, 1 milyondan 92 binden fazla ki\u015fi hayat\u0131n\u0131 kaybetti.<\/p>\n<\/p>\n

Bloomberg HT<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

ABD’li biyoteknoloji \u015firketi Vaxart taraf\u0131ndan geli\u015ftirilen, tablet formunda a\u011f\u0131z yoluyla al\u0131nabilen potansiyel yeni tip koronavir\u00fcs (Kovid-19 …<\/p>\n","protected":false},"author":1,"featured_media":10099,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[367,196,1540,216,276],"class_list":["post-10098","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ekonomi","tag-asama","tag-asi","tag-klinik-deneme","tag-kovid-19","tag-uzerinde"],"yoast_head":"\n